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10/17/2016

My Definition of “Intestinal Starvation”

If you haven’t read these articles below, please read them first.

A Set-Point Weight; The Precondition Regarding the Rebound Effect

Two Meanings to the Phrase 'Gaining Weight'

In my previous article, "Two meanings to the phrase 'gaining weight' ," I wrote that your set-point weight increases by the hunger mechanism-strictly speaking, intestinal starvation. I would like to explain it simply.

  

Of course, in order to gain weight, you need nutrition such as carbohydrates, protein, or fat.

However, it’s what happens later on...because there is a time lag between the emergence of the cause of gaining weight and the actual gaining of weight by eating.

What I mention here as “intestinal starvation” is different from the situation such as when you don't eat anything over a few days.

Definition

(1) It happens when you eat and when your gastrointestinal tract is working.

(2) It refers to the situation between meals, such as between breakfast and dinner, or lunch and late dinner, or dinner and the next lunch, where every substance in the entire intestines from a range of seven to eight meters has been digested.(It might be small intestine only.)

In other words, the stomach and intestines are working to nourish the body, but all the food eaten has been digested, and the body perceives it as “there is no food.” It’s different from simple hunger in that:

 (a) basically, everything, including protein, fat, and even water, is digested;

 (b) there is no fiber or anything close to it (※This is why it is said refined carbohydrates make you fat).

▽Over the course of evolution, humans stored nutrition in the liver, bones, muscles, and fat cells in order to prepare for cases of starvation. This is because they didn’t know when they could eat the next time.

From this aspect, getting fat should be the mechanism of the body trying to store energy. Then this mechanism of storing nutrition should work strongly with those who don’t eat a lot.

However, in this era with an abundance of food, it seems like those who eat a lot are obese and those that don't eat much are thin, and this tends to lead to a misunderstanding.

There is a reason for this, and  it is my own theory based on my personal experience.
The question here is :
"In what way do our bodies perceive starvation ?" Starvation is not decided by the amount of how much we’ve eaten, but rather, how the digestion process in the intestines proceeds.

That is to say, even if you eat a lot, if your diet is skewed toward easily digestible carbohydrates and some protein, and you end up being very hungry for hours, you will be close to a starvation situation.

On the other hand, even if you eat a little, if you eat a well-balanced diet including vegetables, dairy, meat, and fat  every five to seven hours, then your body won’t perceive you as being in starvation mode. When there are some undigested substances in your intestines, your body perceives them as "there is still food." In other words, your intestines decide everything.
  

A long time ago, our ancestors had nuts, meat, or root vegetables, and then, even if they had nothing after that for a whole day, their bodies didn’t perceive it as starvation.

On the other hand, our current bodies sometimes  perceive us in starvation mode depending on what we eat for as little as seven to eight hours

This is an important message to convey that the increase in obesity that has been occurring worldwide since around 1980 is not necessarily due to increased caloric intake, but rather is related to (1) refined carbohydrates and easily digestible food, and (2) irregular eating habits-skipping breakfast or late night meals, etc.-associated with lifestyle changes.

[Related article] Why Does the Body Perceive That It Is More Starved than in the Past?
     

03/15/2016

Two Meanings to the Phrase "Gaining Weight"

Contents

  1. When your weight goes back to your set-point weight  (A)
  2. When your set-point weight itself increases (B)

Please check out my blog below before reading this one.

→ A Set-Point Weight; The Precondition Regarding the Rebound Effect

I would like to define this term first. There are two meanings of the expression "gaining weight" which we use daily. I think the confusion of these meanings causes a lot of misunderstandings.

For example,  “you'll gain weight if you eat a lot of calories” or "despite dieting and eating less, you gain even more weight when you rebound,” etc.

I realized this when I got really thin, but I think the confusion of these two meanings results in various misunderstandings and false information, and most people are dieting in the wrong way.
    

1. When your weight goes back to your set-point weight  (A)

The first one is “gaining weight” meaning to go back to your set-point weight based on the mechanism of maintaining your present condition. 

set-point weight

Many of those who are overweight try to  keep their weight low by reducing their daily caloric intake and/or doing some exercise, because they do not want to gain weight.

In such cases, the body always tries to go back to its set-point. Therefore, it is no surprise that if they stop calorie restriction and return to their previous eating habits, they will gain weight. 

(Note: Temporary overeating may cause a slight increase in weight beyond the set-point, but the set-point itself remains unchanged, and the weight gain can be considered temporary.)

When people say, "If I eat high-calorie foods, I gain weight easily," or "If I eat sweets or cake, I gain weight," they are mostly talking about this meaning. 

Sometimes I hear women say, "I have a body type that gains weight easily as soon as I eat a little more."
But, in my opinion, it means that the body is repeatedly going through a “mini-diet” and a “mini-rebound” by the mechanism to preserve its current stasis.

▷Toru Watanabe, a Japanese actor, used to be heavy, but with a diet, he weighed around 70kg when he appeared on a television show.

However, when he got married at twenty-six, he couldn't maintain his diet anymore and ate a lot and he went back to 130kg. (It is said that he made a new record for his weight change every time he dieted.)

Again with the help of his wife’s home cooking, he succeeded in losing 40kg.

However, in the end, he repeated rebounding. It’s quite a famous story in Japan.
(You can imagine a glass in which water is increasing and decreasing.)

The set-point weight has not changed

2. When your set-point weight itself increases (B)

On the other hand, the second “gaining weight” expression means that your set-point weight itself increases.
Though I have reduced the amount of my food intake, I shattered my previous weight level and gained three kilograms in the last year which means I’ve gained ten kilograms in the last three years... meaning my maximum weight has increased.  
 

The set-point weight increases

This is not due to the amount of food eaten or caloric intake, but by the mechanism of hunger (strictly speaking, I have defined it as “intestinal starvation” ).

I believe that this makes a fundamental difference between fat people and thin/lean people. (You can imagine a glass of water that the glass itself is growing larger.)

[Related article] 
My Definition of “Intestinal Starvation”

For example, someone who has never been more than sixty kilograms has become sixty-three kilograms in the last year. In this case, it means that his/her set-point weight itself increased from sixty to sixty-three kilograms.

When you gain weight to your set-point weight from a rebound after a diet, it's the (A) mechanism, but if you gain weight naturally more than your set-point weight, it is the (B) mechanism. This is because a calorie-restricted diet can create a situation of intestinal starvation.

It is generally believed in Japan that eating when your metabolism is slowing down makes you gain more weight, but it has already been proven that fat people have a higher basal metabolism[1].
     

■Japanese Sumo wrestlers are famous for eating a lot of rice and being fat, but I believe that, to put it in extreme terms, they will gain weight because of a mix of (A) and (B).

Although it looks like they eat more and are gaining weight, the mechanism should be the same as that of people who try dieting, but in the end, they gain more weight than before due to the rebound effect.
       

References:
[1] Dr. Jason Fung, The Obesity Code, 2016, Pages 62.

03/03/2016

The Set-Point Weight; The Precondition Regarding the Rebound Effect

Contents

  1. Each person has the ability to maintain their present condition
  2. Encounter with the set-point theory

1. Each person has the ability to maintain their present condition

First of all, I want to explain the most important point. It's the assumption that each person has the ability to maintain their present condition, also known as preserving current stasis in the body.
I recognize that this is the precondition of everyone regarding weight control.

For example, there are three women:

(A) 48kg・・・who can't gain weight even if she eats a lot.
(B) 58kg・・・who can easily gain two kilos if she lets her guard down and eats a little more.
(C) 85kg・・・                   〃

All through the year, we get thinner when we are busy, and we gain a little fat when we aren’t active and eat a lot. Although everyone repeats the same pattern, even if we don't calculate calories strictly, the body shape of person won't change so easily. Fat people are fat and thin people are thin. 

In other words, I believe that each person has a stable weight based on their body's homeostatic functions, which I initially defined as their "base weight."
     

[Base weight] = The stable weight one returns to after spending 3-5 days relaxing without excessive exercise or work, while consuming calories based on their daily energy needs.
      

However, despite the lack of official proof or definition, some researchers have already used the concepts of 'set-point weight.' Additionally, my "base weight" can be confused with "baseline weight," which is used in some studies. Therefore, I will use 'set-point weight' or ‘set-point’ for body weight going forward."

     
In this example, Person A's set-point weight is forty-eight kilograms. However, for Persons B and C, the weights they quickly revert to when they let their guard down and eat a lot—sixty kilograms and eighty-seven kilograms, respectively—can be considered their actual set-point weight. This means that their homeostatic functions are working to maintain those weights. 


So, it’s difficult to assume a person’s body and weight condition only with caloric intake.

Consider the example above, that if A continues an intake of 100kcal over her recommended daily caloric intake every day for several months or years, the assumption is that it will accumulate into fat and she will eventually gain weight up to the eighty-kilogram level. This is wrong (She might gain weight but that is a different mechanism).


In general, people who are overweight are more likely to be restricting calories and eating modestly, so their current weight is often lower than their set-point weight. On the other hand, thin people don't have caloric restrictions, so their current weight and their set-point weight are often close.
(Temporary overeating may lead to further weight gain beyond the body’s set-point, but I believe this weight gain is temporary and does not alter one’s set- point weight.)

            

set-point weight-1
set-point weight-2

Therefore, ‘thin A’ won't gain weight even if she eats a lot, and B and C will gain weight immediately as soon as they eat a lot.           

▽Example of Hozumi Hasegawa, the professional boxer who defended his title ten times as the twenty-sixth Champion of WBC World bantamweight class.

The Bantamweight limit is fifty-three-point-five kilograms(53.5kg). As his body got older, losing weight became harder. For a defending match, he had to lose more than ten kilograms in a month. 

But, as soon as the match was over and he started to eat, his weight increased ten kilograms in a few days. The rate of going back to his set-point weight was fast. Those who have tried diets and eat less than usual might have experienced this. Often, it's called the rebound effect.
    

2. Encounter with the set-point theory

Most of us do not consciously adjust our daily energy intake and expenditure. Nevertheless, an individual's body weight remains relatively stable.

Individual body weight variance is typically only 0.5% over periods of 6 to 10 weeks[1,2] (Khosha and Billewicz 1964)According to cross-sectional data, weight changes over longer periods of time are still modest, and even diabetic individuals display coefficients of body weight variation of only 3.7– 4.6% over a period of five years[1,3] (Goodner and Oglive 1974)


With the global increase in obesity since the 1970’s, these coefficients of body weight variation may no longer be as accurate. However, many people still stay lean (especially in Asia), and, in fact, even those who are overweight or obese manage to maintain their weight, heavy as they may be, for many years[4]

In other words, despite some fluctuations in weight in daily life, there must be an internal regulatory mechanism that works to keep weight and fat within a certain range over the long haul.

■In recent years, the role of homeostatic regulation has been acknowledged, and there is growing evidence that the body employs physiological mechanisms to control energy balance and maintain body weight at a genetically and environmentally determined "set-point."[5]

When a person loses weight, the body substantially lowers energy expenditure, often more than expected based on changes in body composition or the thermic effect of food.

Additionally, it triggers hormonal changes that increase appetite and modifies food preferences through behavioral adaptations, aiming to restore body weight to its set-point range[6].

This feedback mechanism is known to apply not only to weight loss but also to temporary overeating[7].

set-point model of weight loss

When I started writing this blog, I had no knowledge of the theory about the body's "set-point," but it almost aligned with what I had always believed. I now believe that understanding the set-point theory is crucial in preventing the spread of obesity and proposing effective weight loss methods.

In particular, to explain the global rise in obesity since the 1970’s, I believe it is essential to understand how (I) genetic and biological factors, and (II) environmental and behavioral factors combine to increase the body’s set-point for weight. I believe my intestinal starvation theory can contribute to this understanding.

For more details, please refer to the articles below.

[Related article] 
 The Increasingly Important "Set-Point" Theory of Body Weight
      

References:
[1]Richard E. Keesey, Matt D. Hirvonen. Body Weight Set-Points: Determination and Adjustment. The Journal of Nutrition, Volume 127, Issue 9, 1997, Pages 1875S-1883S, ISSN 0022-3166.

[2]KHOSLA T, BILLEWICZ WZ. MEASUREMENT OF CHANGE IN BODY-WEIGHT. Br J Nutr. 1964;18:227-39. 

[3]Goodner CJ, Ogilvie JT. Homeostasis of body weight in a diabetes clinic population. Diabetes 1974 Apr;23(4):318-26. 

[4] Gary Taubes. 2011. Why we get fat. New York: Anchor books, Page 59.

[5]Egan AM, Collins AL. Dynamic changes in energy expenditure in response to underfeeding: a review. Proc Nutr Soc. 2022 May;81(2):199-212. doi: 10.1017/S0029665121003669. Epub 2021 Oct 4. PMID: 35103583.

[6]Ganipisetti VM, Bollimunta P. Obesity and Set-Point Theory. 2023 Apr 25. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 37276312.

[7]Bray GA.The pain of weight gain: self-experimentation with overfeeding. Am J Clin Nutr. 2020 Jan 1;111(1):17-20.